#Feedback_control_mechanism
Hormones maintain homeostasis in living systems. The feedback control mechanism existing in the interrelation between hormones is also in fact very important in the maintenance of homeostasis. The rate of hormone synthesis and release is controlled by the negative feedback mechanism which is best illustrated by the TRF-TSH interaction.
The #hypothalamus secretes TRF which stimulates the pituitary gland to secrete TSH, which in turn stimulates the thyroid gland to secrete thyroxine. When the amount of thyroxine exceeds the required levels, it exerts a negative feedback effect on the hypothalamus, which reduces the production of TRF, in turn secreting less amounts of TSH. When the amount of TSH is reduced (hyposecretion), naturally thyroid gland also secretes less amount of thyroxine, ultimately bringing back its levels to normal in the body.
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Feedback control mechanism of endocrine glands endocrine glands list | |
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